Whenever Smode notices a problem in your project, it will raise errors or warnings in the issues panel to notify you of the problem and enable you to try resolving it.
Therefore, you shouldn't ignore them. If something isn't working properly in your project, you may be able to find out where the problem lies in this list.
You can access the item affected by the problem directly from this panel to try and resolve it.
Once the problems have been solved, you can clear the list using the button at the top of the panel to notice more easily if any new problems arise.